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Showing 1 to 12 of 151 entries
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The Never-Ending Public Health Issue of Adulterants in Abused Drugs.

Journal of analytical toxicology

Busardò FP, Pichini S, Pacifici R, Karch SB.
PMID: 27368339
J Anal Toxicol. 2016 Sep;40(7):561-2. doi: 10.1093/jat/bkw051. Epub 2016 Jun 30.

No abstract available.

Fragmentation pathways and structural characterization of 14 nerve agent compounds by electrospray ionization tandem mass spectrometry.

Journal of analytical toxicology

Housman KJ, Swift AT, Oyler JM.
PMID: 25519457
J Anal Toxicol. 2015 Mar;39(2):96-105. doi: 10.1093/jat/bku135. Epub 2014 Dec 16.

Organophosphate nerve agents (OPNAs) are some of the most widely used and proliferated chemical warfare agents. As evidenced by recent events in Syria, these compounds remain a serious military and terrorist threat to human health because of their toxicity...

Diagnostic Performance of Triagetrade mark for Benzodiazepines: Urine Analysis of the Dose of Therapeutic Cases.

Journal of analytical toxicology

Kurisaki E, Hayashida M, Nihira M, Ohno Y, Mashiko H, Okano T, Niwa SI, Hiraiwa K.
PMID: 16297284
J Anal Toxicol. 2005;29(6):539-543.

We evaluated the diagnostic performance of Triage for benzodiazepines in 74 urine specimens from outpatients given therapeutic doses of benzodiazepines and compared the results of EMIT assays. Results obtained in all urine samples were confirmed using liquid chromatography-mass spectrometry...

Correction to: Simultaneous Screening and Quantification of Basic, Neutral and Acidic Drugs in Blood Using UPLC-QTOF-MS.

Journal of analytical toxicology

Bidny S, Gago K, Chung P, Albertyn D, Pasin D.
PMID: 28204488
J Anal Toxicol. 2017 Apr 01;41(3):259. doi: 10.1093/jat/bkx016.

No abstract available.

Corrected retention indices in HPLC: their use for the identification of acidic and neutral drugs.

Journal of analytical toxicology

Bogusz M, Aderjan R.
PMID: 3379923
J Anal Toxicol. 1988 Mar-Apr;12(2):67-72. doi: 10.1093/jat/12.2.67.

Thirty-seven selected acidic and neutral drugs were analyzed by HPLC with two-step gradient elution and nine different ODS silica columns. The retention index values (RI) for drugs were calculated against a series of alkyl-arylketones and corrected according to the...

Simultaneous Determination of 5- and 6-APB in Blood, other Body Fluids, Hair, and Various Tissues by HPLC-MS/MS.

Journal of analytical toxicology

Hofmann V, Sundermann TR, Landmann A, Rechtsteiner S, Schmitt G, Bartel M.
PMID: 33576419
J Anal Toxicol. 2021 Feb 12; doi: 10.1093/jat/bkab018. Epub 2021 Feb 12.

5-(2-aminopropyl)benzofuran (5-APB) and 6-(2-aminopropyl)benzofuran (6-APB) are benzofuran analogues of amphetamine and belong to the category of new psychoactive substances (NPS). Despite already published fatal 5- and 6-APB intoxication - in most cases, a combination of both substances - no...

A Single Method for 127 Recommended and Additional DUID Drugs in Blood and Urine by LC-MS/MS.

Journal of analytical toxicology

Farley M, Tran H, Towler S, Gevorkyan J, Pearring S, Rodda LN.
PMID: 34159389
J Anal Toxicol. 2021 Jun 23; doi: 10.1093/jat/bkab075. Epub 2021 Jun 23.

Driving under the influence of drugs (DUID) cases continue to challenge forensic toxicologists as both the volume and complexity of casework increases. Comprehensive DUID testing should also meet the drafted ASB/ANSI standard and the NSC-ADID recommendations. A simple method...

Tentative Identification of Etazene (etodesnitazene) Metabolites in Rat Serum and Urine by Gas Chromatography-Mass Spectrometry and Accurate Mass Liquid Chromatography-Mass Spectrometry.

Journal of analytical toxicology

Grigoryev A, Kavanagh P, Dowling G, Rodin I.
PMID: 34994784
J Anal Toxicol. 2022 Jan 05; doi: 10.1093/jat/bkac001. Epub 2022 Jan 05.

2-Benzylbenzimidazole derivatives comprise a small but forensically significant group of synthetic opioids. In humans, the metabolism of some members of this group is extensive, with little or none of the parent compound remaining. The recent detection of the 2-benzylbenzimidazole...

Urine Drug Screening in the Era of Designer Benzodiazepines: Comparison of Three Immunoassay Platforms, LC-QTOF-MS, and LC-MS/MS.

Journal of analytical toxicology

Puzyrenko A, Wang D, Schneider R, Wallace G, Schreiber S, Brandt K, Gunsolus IL.
PMID: 34557900
J Anal Toxicol. 2021 Sep 24; doi: 10.1093/jat/bkab108. Epub 2021 Sep 24.

This study investigated the presence of designer benzodiazepines in 35 urine specimens obtained from emergency department patients undergoing urine drug screening. All specimens showed apparent false-positive benzodiazepine screening results (i.e., confirmatory testing using a 19-component LC-MS/MS panel showed no...

Detection of Brevetoxin in Human Plasma by ELISA.

Journal of analytical toxicology

Cunningham BR, Coleman RM, Schaefer AM, Hamelin EI, Johnson RC.
PMID: 33515246
J Anal Toxicol. 2021 Jan 30; doi: 10.1093/jat/bkab010. Epub 2021 Jan 30.

Florida red tides have become more common and persistent in and around the Gulf of Mexico. When in bloom, red tides can produce brevetoxins in high concentrations, leading to human exposures primarily through contaminated food and ocean spray. The...

Hair Analysis of Methoxphenidine in a Forensic Chemsex Case.

Journal of analytical toxicology

Goncalves R, Castaing N, Titier K, Dumestre-Toulet V.
PMID: 33523230
J Anal Toxicol. 2021 Feb 01; doi: 10.1093/jat/bkab016. Epub 2021 Feb 01.

Methoxphenidine (MXP, 2-MeO-diphenidine) is a dissociative anaesthetic drug of the diarylethylamine type, recently introduced for recreational purposes through the online-based sale of new psychoactive substances (NPS). The concentration of MXP in hair has never been reported, either in cases...

Methadone, Buprenorphine, Oxycodone, Fentanyl, and Tramadol in Multiple Postmortem Matrices.

Journal of analytical toxicology

Havig SM, Vindenes V, Øiestad ÅML, Rogde S, Thaulow CH.
PMID: 34115841
J Anal Toxicol. 2021 Jun 12; doi: 10.1093/jat/bkab071. Epub 2021 Jun 12.

Peripheral blood concentrations are generally preferred for postmortem toxicological interpretation, but some autopsy cases may lack blood for sampling due to decomposition or large traumas etc. In such cases, other tissues or bodily fluids must be sampled; however, limited...

Showing 1 to 12 of 151 entries